Compile Data Set for Download or QSAR

Found 10 hits of Enzyme Inhibition Constant Data   

TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519495(CHEMBL34023)copy SMILEScopy InChI
Affinity DataKi:  0.00700nMAssay Description:Inhibition of Plasmodium falciparum ADA assessed as reduction in formation of ammonia using adenosine as substrate incubated for 15 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22925((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)copy SMILEScopy InChI
Affinity DataKi:  0.0260nMAssay Description:Inhibition of human erythrocytes ADA assessed as equilibrium dissociation constant by measuring reduction in formation of inosine using adenosine as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMedDrugBank
TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22925((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)copy SMILEScopy InChI
Affinity DataKi:  0.0380nMAssay Description:Inhibition of Plasmodium falciparum N-terminal thrombin cleavable His6-tagged ADA expressed in Escherichia coli BL21 assessed as equilibrium dissocia...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22925((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of human erythrocytes ADA assessed as reduction in formation of inosine using adenosine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMedDrugBank
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22925((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of Plasmodium falciparum N-terminal thrombin cleavable His6-tagged ADA expressed in Escherichia coli BL21 assessed as reduction in formati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor complex formationMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)copy SMILEScopy InChI
Affinity DataKi:  72nMAssay Description:Inhibition of human PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
TargetGMP synthase [glutamine-hydrolyzing](Homo sapiens)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519499(CHEBI:8612 | Psicofuranine)copy SMILEScopy InChI
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of human GMP synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetGMP synthase [glutamine-hydrolyzing](Homo sapiens)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519498(Decoyinine)copy SMILEScopy InChI
Affinity DataIC50: 4.65E+4nMAssay Description:Inhibition of human GMP synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
Displayed 1 to 50 (of 52 total ) | Next | Last >>* indicates data uncertainty>20%